Mr John Findlay

Mr John Findlay

BMedSci (hons) BMBS (hons) PhD FRCS

John is a Consultant Upper GI and Abdominal Wall Surgeon at North Devon District Hospital. He qualified from the University of Nottingham in 2007, awarded a First Class Honours BMedSci for research in molecular genetics and BMBS with honours. He trained in surgery in Oxford, and was appointed as a Consultant in North Devon in 2019. His particular clinical interests are gastro-oesophageal reflux disease and hiatus hernias, oesophageal dysmotility, laparoscopic hernia surgery and complex abdominal wall surgery. John is also Clinical Lead for Upper GI Cancer.

John’s doctoral and post-doctoral research at the University of Oxford focused on augmenting clinical decision-making in Upper GI Surgery using sophisticated modelling and machine learning of high resolution datasets, decision theory, and evidence-based surgery. He received his PhD for genomics and clinical informatics at the Wellcome Trust Centre for Human Genetics and the Department of Oncology, and was an Honorary Clinical Lecturer in Surgery, NIHR Oxford Biomedical Research Centre Senior Clinical Research Fellow in Oesophagogastric Informatics, Lecturer in Clinical Medicine at Corpus Christi College, and Surgical Tutor at the University of Oxford.

John has been awarded 12 international and national research prizes, published more than 60 peer-reviewed papers and book chapters, given over 60 international and national presentations and lectures, and is a Senior Editor at the International Journal of Clinical Practice. His current research focusses on improving clinical outcomes, processes and decision-making in Upper GI and abdominal wall surgery. John also has an interest in motorsport medicine and was a member of the Formula One® British Grand Prix Medical Team. He is a member of the British Hernia Society and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland.

Clinical expertise

  • Gastrooesophageal reflux disease (investigation, treatment and surgery)
  • Barrett’s oesophagus
  • Hiatus hernias
  • Oesophageal dysmotility (including achalasia)
  • Abdominal wall surgery (open and laparoscopic hernia surgery, and abdominal wall reconstruction)
  • Benign biliary surgery

NHS Referrals

Sonia Woodage 01271 322424

Recent Key Publications

Temporal validation of metabolic nodal response of esophageal cancer to neoadjuvant chemotherapy as an independent predictor of unresectable disease, survival, and recurrence

Findlay JM, Dickson E, Fiorani C, Bradley KM, Mukherjee S, Gillies RS, Maynard ND, Middleton MR

European Radiology (2019)

Routinely staging gastric cancer with 18F-FDG PET-CT detects additional metastases and predicts early recurrence and death after surgery.

Findlay JM, Antonowicz S, Zhang A, el Kafsi J, Gillies RS, Bradley KM, Maynard ND, Middleton MR

European Radiology (2019)

Novel imaging techniques in staging oesophageal cancer.

Foley K, Findlay JM, Goh V

Best Practice and Research Clinical Gastroenterology (2018)

Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma

MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM
Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma R

Scientific Reports (2018)

Prophylactic mesh reinforcement of stomas: a cost-effectiveness meta-analysis of randomized controlled trials

Findlay JM, Wood C, Cunningham C

Techniques in Coloproctology (2018)

Metabolic nodal response to neoadjuvant therapy—a new and independent predictor of prognosis after surgery for oesophageal cancer

Findlay JM, Bradley KM, Wang LM, Franklin JM, Teoh EJ, Gleeson FV, Maynard ND, Gillies RS,
Middleton MR

British Journal of Surgery (2017)

Predicting pathologic response of esophageal cancer to neoadjuvant chemotherapy: the implications of metabolic nodal response for personalized therapy.

Findlay JM, Bradley KM, Wang LM, Franklin JM, Teoh EJ, Gleeson FV, Maynard ND, Gillies RS,
Middleton MR

Journal of Nuclear Medicine (2017)

Multimodality treatment for esophageal adenocarcinoma: multi-center propensity-score matched study

Markar SR, Noordman BJ, Mackenzie H, Findlay JM, Boshier PR, Ni M, Steyerberg EW,
van der Gaast A, Hulshof MCCM, Maynard N, van Berge Henegouwen MI, Wijnhoven BPL, Reynolds JV, Van Lanschot JJB, Hanna GB

Annals of Oncology (2017)

Non-operative management of appendicitis in adults: a systematic review and meta-analysis of randomized controlled trials.

Findlay JM, el Kafsi J, Hammer C, Gilmour J, Gillies RS, Maynard ND

Journal of the American College of Surgeons (2017)

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.

Findlay JM, Castro-Giner F, Makino S, Rayner E, Kartsonaki C, Cross W, Kovac M, Ulahannan D,
Palles C, Gillies RS, MacGregor TP, Church D, Maynard ND, Buffa F, Cazier JB, Graham TA,
Wang LM, Sharma RA, Middleton M, Tomlinson I

Nature Communications (2016)

Restaging oesophageal cancer after neoadjuvant therapy with 18F-FDG PET-CT: identifying interval metastases and predicting incurable disease at surgery.

Findlay JM, Gillies RS, Franklin JM, Teoh EJ, Jones GE, di Carlo S, Gleeson FV, Maynard ND,
Bradley KM, Middleton MR

European Radiology (2016)

Pragmatic staging of oesophageal cancer using decision theory involving selective endoscopic ultrasonography, PET and laparoscopy.

Findlay JM, Bradley KM, Maile EJ, Braden B, Maw J, Phillips-Hughes J, Gillies RS, Maynard ND,
Middleton MR

British Journal of Surgery (2016)

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett’s esophagus

Palles C, Chegwidden L, Li X, Findlay JM …. Tomlinson I, Jankowski

Journal of Gastroenterology (2015)

A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.

Findlay JM, Middleton MR, Tomlinson

Annals of Oncology (2015)

Enhanced recovery for esophagectomy: a systematic review and evidence-based guidelines Findlay JM, Gillies RS, Millo J, Sgromo B, Marshall RE, Maynard ND
Annals of Surgery (2014)

BOOK CHAPTERS

Pathophysiology and investigation of gastrooesophageal reflux disease

Findlay JM, Maynard ND

In: Oesophagogastric Surgery: A Companion to Specialist Surgical Practice 6th Ed (2018)

Common Variants Confer Susceptibility to Barrett’s Esophagus: Insights from the First Genome-Wide Association Studies

Palles C, Findlay JM, Tomlinson I

In: Stem Cells, Pre-neoplasia, and Early Cancer of the Upper GI Tract (2016)

Pathophysiology and investigation of gastrooesophageal reflux disease.

Findlay JM and Maynard ND

In: Oesophagogastric Surgery: A Companion to Specialist Surgical Practice 5th Ed (2013)

Last updated: May 5, 2020