Bone marrow examination
Specimen collection (including ‘Maximum Times for Add-on Requests’)
HIV Monitoring (CD4 & HLA-B27 Testing Advice
Bone marrow examination
Indications for bone marrow examination should be discussed with the Consultant Haematologist.
|The initial investigation of a Patient with a bleeding tendency should comprise: –|
Full Blood Count ( includes platelets ),
Prothrombin Time ( PT )
Partial Thromboplastin Time ( APTT )
If DIC is suspected, Fibrinogen and D-Dimers should be added. Further investigation should be discussed with the Consultant Haematologist.
|Heritable Thrombophilia – Guidelines for Testing|
|Recommendations of who should be investigated for inherited thrombophilia can be found here. If there are any concerns about the eligibility for testing, please discuss with a Consultant Haematologist, ext 3198 (01271 349198).|
Clinical advice relating to anticoagulation management can be found in the Trust’s Oral Anticoagulation Policy and referenced documents within that policy.
HIV Monitoring and HLA-B27 Testing
HIV monitoring testing is by way of CD4 counts only. For clinical advice in respect of when and how to request these tests and how to interpret the results please contact Consultant Immunologist, Derrifird Hospital Plymouth, Dr Claire Bethune firstname.lastname@example.org. The contact in North Devon is Dr Elizabeth Claydon:- email@example.com.
Please note that whilst the laboratory issues CD4 count results with a reference range we do not provide ‘High’ or ‘Low’ flags against results at the request of Dr Claydon.
HLA-B27 testing: For clinical advice in respect of when and how to request this test and how to interpret the results please contact Consultant Rheumatologist, North Devon District Hospital, Dr Stuart Kyle firstname.lastname@example.org
Blood specimen tube guides are available here.
General specimen collection information can be found here.
Time Limits for Requesting Additional Examinations
|Maximum times for Add-on Requests – Haematology Samples|
|Add-on test||Primary sample required||Max. time post sampling|
|Plasma Viscosity||Purple tube||4 days|
|Blood film||Purple tube||1 day|
|Malaria screen||Purple tube||4 hours|
|Reticulocyte count||Purple tube||12 hours|
|G6PD||Purple tube||4 days|
|Hb electrophoresis||Purple tube||4 days|
|Glandular fever screen||Purple tube/Gold tube||24 hours/4 days|
|Cell markers||Purple tube||12 hours|
|APTT||Blue tube||4 hours|
|D Dimer||Blue tube||24 hours|
|GHB||Purple tube||4 days|
|Coag screen||Blue tube||4 hours|
|IF Antibodies||Gold tube||4 days|
|Maximum Times for Add-on Requests – Blood Transfusion Samples|
|All Blood Transfusion samples are retained for 7 days. However, the issue of blood against a Group & Save sample is dependent on recent transfusion history. Please see the Blood Transfusion Policy or contact the Transfusion Laboratory for further details.|